Metabolic syndrome is defined as a cluster of conditions that together concur to increase cardiovascular risk; its development is the wake-up call for obesity and other cardiometabolic diseases now considered as the major public burden. Microbiota seems to play a key role in metabolic syndrome since a dysbiotic status can compromise some cardio-metabolic receptors increasing the incidence of cardiovascular disease risks.
Few clinical trials reported positive results, but most of them only focused on cholesterol reduction without mentioning other important parameters as visceral fat or blood pressure. From this perspective, L. plantarum PBS067, L. reuteri PBS072 and L. acidophilus PBS066, have been extensively studied in-vitro and clinically, demonstrating a beneficial effect in terms of waist circumferences, visceral fat and quality of life, providing not only a short- term effect on body shape, but a more comprehensive pro-healthy approach to prevention, delivering long-term outcomes through local microbiota modulation.
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