What is it?SelectSIEVE®Apple PCQ is an active ingredient based on balanced and highly standardized polyphenols from apple.
Biological targetPeople affected by hyperglycemia or subjected to high risk of cardiovascular disease due to overweight.
Mechanism of action
- Reduction of calories intake through competitive inhibition of intestinal glucose absorption due to the Phloridzinbond to the SGLT1/GLUT transporters
- Regulation of hepatic glycaemia through modulation of the G6P-translocase activity by chlorogenicacid
- Increase of draining through the improvement of blood circulation due to vasculoprotectorand veinotonicaction of flavonoids
- Limitation of fat storage due to the repression of the PPAR-γ gene (differentiation of pre-adipocytes into mature adipocytes) then reducing fat storage
- Metabolic effect by improving the endothelial reactivity and reducing the serum uric acid