Project Description

PrincipHYAL® Cube3

Efficacy, to the power 3


PrincipHYAL® Cube3 shows:

  • a quick lifting effect elasticity, smoothness, wrinkleless, depth of wrinkles, synthesis of neo-elastin, improvement of skin aspects
  • a quick penetration of actives enhanced skin penetration of both liposoluble or hydrosoluble ingredients
  • a quick moisturization better epidermis health, barrier effect, moisturization


Sodium Hyaluronate is a linear polymer characterized by an ensemble of parameters in which molecular weight plays an important role.
However, PrincipHYAL® Cube3 is based on a full spectrum of molecule lengths. It mimics the complexity of a complete range of fractions working in synergy, just as naturally found in our body.

What is it?

PrincipHYAL® Cube3 is a full-spectrum biotechnological fraction of sodium hyaluronate that targets short-term anti-aging effects.

What does it do?

PrincipHYAL® Cube3 improves skin aspect (immediate lifting, smoothed, healthier, more hydrated, re-structured) and could enhance formula activity.

Biological target

Tired or aging skins are directly related to the appearance of surface irregularities and small wrinkles. Besides internal factors (genetics, lifestyle), other parameters such as dehydration or loss of elasticity have to be considered.
PrincipHYAL® Cube3 is a biotechnological ingredient that reproduces a specific spectrum of molecular weight, with a targeted focus on skins at a particular physiological step (homeostasis or stress).

Mechanism of action

Treated skins react in a more adapted manner, thanks to an evolutive interaction between matrix hyaluronans and their cell receptor CD44. This adaptive answer gives to the cell a capacity to “sense” its microenvironment and respond in return (by signal transduction or by cytoskeletal dynamics regulation). The benefit for final consumers? A better effect linked to a more specific cellular answer.


  • Anti-aging / firming
  • Anti-wrinkles / Preage
  • Booster of skin penetration
  • Hydration (short term)
  • Matrix degradation