Project Description


Bring back the natural serenity of your skin


PhytoSerene was tested in-vitro & in-vivo on its performances, and demonstrated:

  • a capacity to improve skin barrier effect after stress
  • a capacity to consequently improve skin moisturization
  • a quick capacity to diminish erythema index (15 minutes to 2 hours)
  • a capacity to help diminish skin redness after submission to a stress


Pine trees protect themselves with a variable thickness of bark around the trunk.
This natural physical shield is doubled with a molecular shield of a pool of natural compounds that helps preventing from external factors. Among these, beta-sitosterol plays an important role in preserving an untroubled state.

What is it?

PhytoSerene is an extremely pure beta-sitosterol, a natural micro-nutrient plant fat which is found in the cells and membranes of the tree. Chemically very similar to animal fat cholesterol, this plant sterol is totally different in its biological function, but because the humans do not synthesize sterols in the body, it is necessary to replace daily losses.

What does it do?

PhytoSerene demonstrates the capacity to reduce the skin redness after exposure to a chemical agent and diminish the TEWL forming a barrier.

Biological target

It usually takes around 21 days for the cells produced at the base of our epidermis (stratum basale) to differentiate and migrate up to the upper part (stratum corneum) to be finally exfoliated.

As skin ages, the cycles of regeneration of epidermis cells are deregulated.
Changes in thickness consequently appear, and our skin looses its suppleness, its elasticity.

Mechanism of action

Scientific research has shown that beta-sitosterol appears to have a vitamin-like action on the functioning of the immune system. It also reduces the release of some pro-inflammatory cytokines, inhibits STAT1, and increases anti-inflammatory IL10 while inhibiting the translocation of NF-kB to the nucleus.


  • Hydration (short term)
  • Protection
  • Skin cohesion
  • Skin inflammation