HA Tech 2.0® is a fine-tuning process that allows to obtain HA with a MW distribution designed for specific applications.

Thanks to this proprietary molecular weight spectrum, ROELMI HPC has developed the PrincipHYAL®line, based on the precise regulation of cultivation conditions for reproducibility and bioprocess optimization. By controlling pH, temperature, dissolved oxygen, pressure, and oxygen transfer, greater process scalability is achieved. It minimizes cross-contamination and unwanted impurities.

PrincipHYAL® line, consisting of:

  • Signal-10 (2-10 kDa): Small MW spectrum with high hydration and firming effect
  • Aurora (30-90 kDa): Precise MW spectrum with skin cohesion improvement effect
  • Difference (50-2500 kDa): Wide MW spectrum with skin healthy aging efficacy
  • Cube3 (50-3000 kDa): Wide MW spectrum with lifting effect and triple action on crow’s feet area